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MUC6(LBP1-MUC6)
产品的序号:IM398克隆号:LBP1-MUC6同型:鼠单克隆表面抗原IgG1細胞市场定位:細胞浆用于团体: 石蜡/冻冰呈阳性剖析: 胃抗体阳性孵育日子: 30-60min抗原复原: 热复原(EDTA)备案表号:粤穗械备2019138六号
临床意义
粘蛋白是一组高分子量的糖蛋白,其合成和分泌是腺上皮组织的特征之一。在生理状态下MUC-2只表达于正常肠粘膜中,又称肠型黏液;MUC-5AC和MUC-6只在正常胃粘膜中表达,又称为胃型黏液,MUC-5AC主要分布在浅层粘膜上皮细胞,而MUC-6分布于粘膜深层腺体细胞。
参考文献
1.Rakha EA, et al. Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6)and their prognostic signifcance in human breast cancer. Mod Pathol. 2005; 18:1295-304.2.Do SI. et al. Associations between the Expression of Mucins (MUC1, MUC2, MUC5AC, and MUC6) and Clinicopathologic Parameters of Human Breast Ductal Carcinomas. J of Breast Cancer. 2013; 16:152-8.3.Mino-Kenudson M, et al. Mucin expression in Betge J. et al. MUC1, MUC2, MUC5AC and MUC6 in colorectal cancer: expression profles and clinical signifcance. Virchows Arch.2016; 469:255-65.